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B7H3 (CD276) Human Gene Knockout Kit (CRISPR)

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SKU
KN215064RB
CD276 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "B7H3 or AK075549"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol B7H3
Locus ID 80381
Components

KN215064G1, B7H3 gRNA vector 1 in pCas-Guide CRISPR vector

KN215064G2, B7H3 gRNA vector 2 in pCas-Guide CRISPR vector

KN215064RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001024736, NM_025240, NM_001329628, NM_001329629
UniProt ID Q5ZPR3
Synonyms 4Ig-B7-H3; B7-H3; B7H3; B7RP-2
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
GA112946 CD276 CRISPRa kit - CRISPR gene activation of human CD276 molecule 1 kit
$1,657.00
KN215064 CD276 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215064BN CD276 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215064LP CD276 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415064 CD276 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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