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FOXP2 Human Gene Knockout Kit (CRISPR)

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SKU
KN214963BN
Foxp2 is a protein that, in humans, is encoded by the FOXP2 gene. OriGene offers FOXP2 human gene knockout kit via CRISPR, also HDR mediated.
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "FOXP2 or AF493430"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Target Symbol FOXP2
Locus ID 93986
Components

KN214963G1, FOXP2 gRNA vector 1 in pCas-Guide CRISPR vector

KN214963G2, FOXP2 gRNA vector 2 in pCas-Guide CRISPR vector

KN214963BND, donor DNA containing left and right homologous arms and functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001172766, NM_001172767, NM_001172777, NM_014491, NM_148898, NM_148899, NM_148900, NR_033766, NR_033767
UniProt ID O15409
Synonyms CAGH44; SPCH1; TNRC10
Summary This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.provided by RefSeq, Feb 2010
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Documents
Resources
Other Versions
SKU Description Size Price
GA114311 FOXP2 CRISPRa kit - CRISPR gene activation of human forkhead box P2 1 kit
$1,657.00
KN214963 FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214963LP FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214963RB FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414963 FOXP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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