Human FOXP2 activation kit by CRISPRa

SKU
GA114311
FOXP2 CRISPRa kit - CRISPR gene activation of human forkhead box P2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FOXP2
Locus ID 93986
Components

GA114311G1, FOXP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114311G2, FOXP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114311G3, FOXP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001172766, NM_001172767, NM_001172777, NM_014491, NM_148898, NM_148899, NM_148900, NR_033766, NR_033767
UniProt ID O15409
Synonyms CAGH44; SPCH1; TNRC10
Summary This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.provided by RefSeq, Feb 2010
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN214963 FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214963BN Foxp2 is a protein that, in humans, is encoded by the FOXP2 gene. OriGene offers FOXP2 human gene knockout kit via CRISPR, also HDR mediated. 1 kit
$1,657.00
KN214963LP FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214963RB FOXP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414963 FOXP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products