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HMGA2 Human Gene Knockout Kit (CRISPR)

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SKU
KN214629BN
HMGA2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "HMGA2 or NM_001015886"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol HMGA2
Locus ID 8091
Components

KN214629G1, HMGA2 gRNA vector 1 in pCas-Guide CRISPR vector

KN214629G2, HMGA2 gRNA vector 2 in pCas-Guide CRISPR vector

KN214629BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001015886, NM_001300918, NM_001300919, NM_001330190, NM_003483, NM_003484
UniProt ID P52926
Synonyms BABL; BABL, LIPO, HMGIC, HMGI-C; high-mobility group (nonhistone chromosomal) protein isoform I-C; High-mobility group protein HMGI-C; high mobility group AT-hook 2; HMGI-C; HMGIC; LIPO; STQTL9
Summary This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA105409 HMGA2 CRISPRa kit - CRISPR gene activation of human high mobility group AT-hook 2 1 kit
$1,657.00
KN214629 HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214629LP HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214629RB HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414629 HMGA2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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