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HMGA2 Rabbit Polyclonal Antibody

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SKU
TA308757
Rabbit polyclonal antibody to HMGA2 (high mobility group AT-hook 2)
Size:
100 ul
Conjugation:
Unconjugated
  $665.00
2 Weeks*
Bulk/Customize

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View other "HMGA2 or NM_003484" antibodies

Specifications
Specifications
Product Data
Application IF, IHC, IP, WB
Recommended Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
Reactivity Human (Predicted: Pig)
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926)
Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 12 kDa
Gene Name high mobility group AT-hook 2
Database Link
Background This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq
Synonyms BABL; HMGI-C; HMGIC; LIPO; STQTL9
Note Seq homology of immunogen across species: Pig (88%)
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome
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Documents
Resources

file-alt Citations

The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in the human kidney
Kha, Krawczyk, Choong et al
Am J Physiol Renal Physiol (2023) 324 (1), F75-F90 DOI: 10.1152/ajprenal.00196.2022
Cited by 5
AI Summary: OriGene’s HMGA2 antibody (catalog no. TA308757) was used in this study to assess HMGA2 protein expression, helping to demonstrate that SOX9 regulates HMGA2 levels in human kidney cells following injury.
Snippet: RRID: AB_2275453), LBR (1:2,000, no. HPA049840, Atlas Antibodies, RRID: AB_2680908), HMGA2 (1:500, no. TA308757, OriGene), HIPK3 (1:25, no. HPA028069, Atlas Antibodies, RRID: AB_10601815), and phospho-MET (1:100, no. 3077, Cell Signaling Technology, RRID: AB_2143884)
IHC
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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