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Human HMGA2 activation kit by CRISPRa

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SKU
GA105409
HMGA2 CRISPRa kit - CRISPR gene activation of human high mobility group AT-hook 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308757 Rabbit polyclonal antibody to HMGA2 (high mobility group AT-hook 2)
100 ul
$665.00
RC214629 HMGA2 (Myc-DDK-tagged)-Human high mobility group AT-hook 2 (HMGA2), transcript variant 1
10 ug
$150.00

Other products for "HMGA2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HMGA2
Locus ID 8091
Components

GA105409G1, HMGA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105409G2, HMGA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105409G3, HMGA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001015886, NM_001300918, NM_001300919, NM_001330190, NM_003483, NM_003484
UniProt ID P52926
Synonyms BABL; BABL, LIPO, HMGIC, HMGI-C; high-mobility group (nonhistone chromosomal) protein isoform I-C; High-mobility group protein HMGI-C; high mobility group AT-hook 2; HMGI-C; HMGIC; LIPO; STQTL9
Summary This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN214629 HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214629BN HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214629LP HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214629RB HMGA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414629 HMGA2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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