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RTEL1 Human Gene Knockout Kit (CRISPR)

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SKU
KN214507BN
RTEL1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol RTEL1
Locus ID 51750
Components

KN214507G1, RTEL1 gRNA vector 1 in pCas-Guide CRISPR vector

KN214507G2, RTEL1 gRNA vector 2 in pCas-Guide CRISPR vector

KN214507BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

Homologous arm and mBFP-Neo sequences:

pUC vector backbone in gray; Left arm sequence in blue; mBFP-Neo in green; Right arm in violet

CTCCAGCCAG CCAGGAGGGC AGAGGGCTGG AGAGGCAGGG CCGGAGGTTC AGACCCTCCG CTCTGACGTT GCGCCTGGTG AGGCCGGGAG GGGTGCCGCT TGCCTCTTCA GCCCTCACGC TCTTGTGGAA GTCGCGGAAT TACTGCAGGC GGAACTTGCA GCACTGTGGG CGTCTTTTCC AGAGAAGGAC GGAGTTGTGG GGCGGGAGGA TAAGGCAAGG CCCAGCCACT TCGCATCTTC GCCCCGCCAG CTCCTCGAGA TGGGATATAC CAGGGTTGCT CTCCAACCCT CTCCGCAGGA GGGACTGATG GAAACGCCTG GGAAAGTAGC CCGGTACCCA CAAAGGCTGT CTACAAACAG AGTCTTACTG TCTTTCCCAG GTCTGTGCCA TAGGGATTCT CGAAGAGAAC AGCGTTGTGT CCCAGTGCAC ATGCTCGCAT CGCTTACCAG GAGTGCCCGA GACCCTAAGA TGTTCGGAGT GGTTTTTTCG CACAGACCCG AATAGCCTGC CCCTCAGCCA CGCTCTGTGC CCTTCTGAGA ACAGGCTGAT AGGTAGAGCA CAGGCCCCGA GGAAAGGACT GCGGGTGGGT GGAGCTTCAG CCAGGACGGG GTGTGCTTCC CTCTCCCGGC CCATTCCAGC CAGGCCCCTC CGGGCCAGAG GCAGCGTCTG TCATAAAAAG GGCTGGTGTT CCAGGTGGGG TCAGAGAGAG GATTGACAAG TAAAAACGAT CGTCCTTTGA AGGGGGCCGG CCCCTCCACA CCTGTGGGTA TTTCTCATCA GGCGGGACGA GAGACTGAGA AAATGAATAA GACACAGAGA CAAAGTATAG AGAGAAAAGT GGGCCCAGGG GACCGGCGCT CAGCATACAG AGGACCTGCA CCGGCACCAG TCTCTGAGTT TCCTCAGTAT TCATTAATTA CTATTTTCAC TATCTCAGCA AGAGGAATGC GGCAGGACAG CAAGGTGATA GTGGGGAGAA GGTCAGCAAG AAAACGTGAG CAAAGGAATC TGGGTCACAA ATAAGTTCAA GGGAAGGTAC TATGCCTGGA TGTGCACGTA GGCTAGTTTT ATGCTTTTCT CCACCCAAAC ATCTCGGTGG

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001283009, NM_001283010, NM_016434, NM_032957
UniProt ID Q9NZ71
Synonyms C20orf41; DKCA4; DKCB5; NHL; RTEL
Summary This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2013
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Documents
Resources
Other Versions
SKU Description Size Price
GA109973 RTEL1 CRISPRa kit - CRISPR gene activation of human regulator of telomere elongation helicase 1 1 kit
$1,657.00
KN214507 RTEL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214507LP RTEL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214507RB RTEL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414507 RTEL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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