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HCP1 (SLC46A1) Human Gene Knockout Kit (CRISPR)

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SKU
KN214417RB
SLC46A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "HCP1 or NM_001242366"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol HCP1
Locus ID 113235
Components

KN214417G1, HCP1 gRNA vector 1 in pCas-Guide CRISPR vector

KN214417G2, HCP1 gRNA vector 2 in pCas-Guide CRISPR vector

KN214417RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001242366, NM_080669
UniProt ID Q96NT5
Synonyms G21; HCP1; PCFT
Summary This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2013
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Other Versions
SKU Description Size Price
GA114397 SLC46A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 46 member 1 1 kit
$1,657.00
KN214417 SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214417BN SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214417LP SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414417 SLC46A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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