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Human HCP1 (SLC46A1) activation kit by CRISPRa

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SKU
GA114397
SLC46A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 46 member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA334591 Rabbit Polyclonal Anti-SLC46A1 Antibody
100 ul
$490.00
RC214417 SLC46A1 (Myc-DDK-tagged)-Human solute carrier family 46 (folate transporter), member 1 (SLC46A1)
10 ug
$457.00

Other products for "SLC46A1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SLC46A1
Locus ID 113235
Components

GA114397G1, HCP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114397G2, HCP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114397G3, HCP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001242366, NM_080669
UniProt ID Q96NT5
Synonyms G21; HCP1; PCFT
Summary This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN214417 SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214417BN SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214417LP SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214417RB SLC46A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414417 SLC46A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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