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TPR Human Gene Knockout Kit (CRISPR)

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SKU
KN214233
TPR - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol TPR
Locus ID 7175
Components

KN214233G1, TPR gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GGCGGTGTTGCAGCAAGTCC

KN214233G2, TPR gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: AGTTTGTTCTGGACAGACTT

KN214233D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

ATGCCCTCTA GTGGCTCAGT GTCCAGAAGC CGCCAACGAG GACGATCCAT GGCATCCCGG GGCTTTGACG GTAAGGTCAC CAGCTCTTCA GGGAGGGCCA AGGGGTGACG AGTACGTATG TGGCGCCACC GTGCGGACAG CGGTTACGGG GCCGAGATAG GAGAGCCAGG GGAGCGGGGA GAAAAACGGA AGCTGAGAGG GCGGTGCAGC ATTGGGCTCC CGGAAAAGAA TGAGAAAAAC ACTACATTTC CCAGAGCCCT ACAAGGCCTG AAGTGGGTGG AGCTGGAAGC CGGAAAATTG GGTGCGCAAG AGGATCAGGG ATAGCCTCTG AGCTCGGGTT CCCAGGGTTC GTAGCTTCCA ACGGCTGCGC GCGCACTTCG GTCGCGGGCG GTGAGGTGCT GTTGCTGAAA CGCTGCCGCT GAGGGTGGAC TCGATTTCCC AGGGTCCCGC CGCGGGAGTC TCCGGCGGGC GGGCGCGCGC GAGCCACCGA GCGAGGTGAT AGAGGCGGCG GCCCAGGCGT CTGGGTCCTG CTGGTCTTCG CCTTTCTTCT CCGCTTCTAC CCCGTCGGCC GCTGCCACTG GGGTCCCTGG CCCCACCGAC GAAAAGTTCC TTGCTGATCA GCAATCCGAG ATCGATGGCC TGAAGGGGCG GCATGAGAAA TTTAAGGTGG AGAGCGGTAA GTGAGATGCT CTTTCCGTCC TTGGTTTTGG GCTCGACTCC CGCCCTTTGG GTCTGGTCTT CCCCCATCAA GTTGGCACTG GGTACCGCTC TGTTAACCTC ACTTCCTGGG CTCTGTGGAT ATCCTGAGCC TTCGCTTTCC TGCTCCTTAC AGTTTGATAA GAAGCCTTTG AAAAAAAAAT CTGAATCTAA GTTCAGTAGC ATTTTCTTTG TAGTTAGGGT AGGCTCATAC AGGGACGCTT ATTTTCCTTC GTCCGGCAGA CGGGAAACAG ACTTGATAGA GTCTGCGAAC CCATCTCTCT AAGCCTAGAG TACCTTATAT GTTTTGTTGC ACTTCAACTG ATAGTGGCTC CGCCCTATTT TCTAGGCACC TGCATTCTAG GCCTTTGCCA AATTGACCAC TCTGTGCACT TGTTCTTAGT GTGTGCGTCG TCCCGTGGCT CCAGAACGAA TCAGATGTTT ACAAAAATGA ATATTAGGTG CATAAGAGCG CTGGAAACAC AGTGAATGTG CAGTACATAA

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003292
UniProt ID P12270
Synonyms nuclear pore complex-associated protein TPR; nucleoprotein TPR; OTTHUMP00000033584; translocated promoter region (to activated MET oncogene); tumor potentiating region
Summary This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA104959 TPR CRISPRa kit - CRISPR gene activation of human translocated promoter region, nuclear basket protein 1 kit
$1,657.00
KN214233BN TPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214233LP TPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214233RB TPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414233 TPR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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