PTP rho (PTPRT) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | PTP rho |
| Locus ID | 11122 |
| Components |
KN213847G1, PTP rho gRNA vector 1 in pCas-Guide CRISPR vector KN213847G2, PTP rho gRNA vector 2 in pCas-Guide CRISPR vector KN213847BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_007050, NM_133170 |
| UniProt ID | O14522 |
| Synonyms | RPTPrho |
| Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
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Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA107648 | PTPRT CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type T | 1 kit |
$1,657.00
|
|
| KN213847 | PTPRT - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN213847LP | PTPRT - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN213847RB | PTPRT - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN413847 | PTPRT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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