PTP rho (PTPRT) Rabbit Polyclonal Antibody

SKU TA322446

Anti-PTPRT Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human ovarian cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 900-915 amino acids of Human protein tyrosine phosphatase, receptor type, T
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: protein tyrosine phosphatase, receptor type T
• Database Link:
  NP_008981
  O14522
• Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region; a single transmembrane region; and two tandem intracellular catalytic domains; and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain; Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene; which encode distinct proteins; have been reported.
• Synonyms: RPTPrho

Reference Data