Tau (MAPT) Human Gene Knockout Kit (CRISPR)

SKU
KN213312BN
MAPT - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Tau
Locus ID 4137
Components

KN213312G1, Tau gRNA vector 1 in pCas-Guide CRISPR vector

KN213312G2, Tau gRNA vector 2 in pCas-Guide CRISPR vector

KN213312BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001123066, NM_001123067, NM_001203251, NM_001203252, NM_005910, NM_016834, NM_016835, NM_016841, NM_173727
UniProt ID P10636
Synonyms DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Summary This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA102816 MAPT CRISPRa kit - CRISPR gene activation of human microtubule associated protein tau 1 kit
$1,657.00
KN213312 MAPT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213312LP MAPT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213312RB MAPT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413312 MAPT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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