LGR5 Human Gene Knockout Kit (CRISPR)

CAT#: KN212825LP

LGR5 - human gene knockout kit via CRISPR, HDR mediated

Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD mBFP-Neo

HDR-mediated knockout kit validation

  See Other Versions

USD 1,657.00

4 Weeks*

    • 1 kit

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Frequently bought together (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

USD 450.00

Anti-LGR5 mouse mAb, clone OTI2A2, PE conjugated
    • 100 ul

USD 494.00

LGR5 (Myc-DDK-tagged)-Human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5)
    • 10 ug

USD 1,245.00

Other products for "LGR5"


Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol LGR5
Locus ID 8549

KN212825G1, LGR5 gRNA vector 1 in pCas-Guide CRISPR vector

KN212825G2, LGR5 gRNA vector 2 in pCas-Guide CRISPR vector

KN212825LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001277226, NM_001277227, NM_003667, NR_110596
UniProt ID O75473
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Summary The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.