LGR5 Human Gene Knockout Kit (CRISPR)

SKU
KN212825BN
LGR5 - human gene knockout kit via CRISPR, HDR mediated
file-pdf HDR-mediated knockout kit validation
Special Offer: Get a $300/€300 discount on this product. Use code: "KN300".
Functional Cassette:
mBFP-Neo GFP-puro Luciferase-Puro RFP-BSD
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  $1,657.00
4 Weeks*
Size

Frequently Bought Together (3)

TA400001 Anti-LGR5 mouse mAb, clone OTI2A2, PE conjugated 100 ul
$494.00
RC212825 LGR5 (Myc-DDK-tagged)-Human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5) 10 ug
$1,245.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg) 10 ug
$450.00

Other products for "LGR5"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol LGR5
Locus ID 8549
Components

KN212825G1, LGR5 gRNA vector 1 in pCas-Guide CRISPR vector

KN212825G2, LGR5 gRNA vector 2 in pCas-Guide CRISPR vector

KN212825BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001277226, NM_001277227, NM_003667, NR_110596
UniProt ID O75473
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Summary The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
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Documents
Resources
Other Versions
SKU Description Size Price
GA105663 LGR5 CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing G protein-coupled receptor 5 1 kit
$1,657.00
KN212825 LGR5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212825LP LGR5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212825RB LGR5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN412825 LGR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.