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Estrogen Receptor beta (ESR2) Human Gene Knockout Kit (CRISPR)

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SKU
KN212665LP
ESR2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Estrogen Receptor beta or NM_001040275"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Estrogen Receptor beta
Locus ID 2100
Components

KN212665G1, Estrogen Receptor beta gRNA vector 1 in pCas-Guide CRISPR vector

KN212665G2, Estrogen Receptor beta gRNA vector 2 in pCas-Guide CRISPR vector

KN212665LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001040275, NM_001040276, NM_001214902, NM_001214903, NM_001271876, NM_001271877, NM_001291712, NM_001291723, NM_001437, NR_073496, NR_073497, NR_073505
UniProt ID Q92731
Synonyms ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2
Summary This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA101462 ESR2 CRISPRa kit - CRISPR gene activation of human estrogen receptor 2 1 kit
$1,657.00
KN212665 ESR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212665BN ESR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212665RB ESR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN412665 ESR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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