FUT8 Human Gene Knockout Kit (CRISPR)

SKU KN212345LP

FUT8 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: FUT8
• Locus ID: 2530
• Components:

  KN212345G1, FUT8 gRNA vector 1 in pCas-Guide CRISPR vector

  KN212345G2, FUT8 gRNA vector 2 in pCas-Guide CRISPR vector

  KN212345LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_004480, NM_178154, NM_178155, NM_178156, NM_178157, NR_038167, NR_038170
• UniProt ID: Q9BYC5
• Synonyms: MGC26465
• Summary: This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
• Shipping: Ambient