Human FUT8 activation kit by CRISPRa

SKU GA101679

FUT8 CRISPRa kit - CRISPR gene activation of human fucosyltransferase 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FUT8
• Locus ID: 2530
• Components:

  GA101679G1, FUT8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101679G2, FUT8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101679G3, FUT8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004480, NM_178154, NM_178155, NM_178156, NM_178157, NR_038167, NR_038170
• UniProt ID: Q9BYC5
• Synonyms: MGC26465
• Summary: This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]