c Rel (REL) Human Gene Knockout Kit (CRISPR)

SKU
KN211878LP
REL - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol c Rel
Locus ID 5966
Components

KN211878G1, c Rel gRNA vector 1 in pCas-Guide CRISPR vector

KN211878G2, c Rel gRNA vector 2 in pCas-Guide CRISPR vector

KN211878LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001291746, NM_002908
UniProt ID Q04864
Synonyms C-Rel
Summary This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2014
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Other Versions
SKU Description Size Price
GA104063 REL CRISPRa kit - CRISPR gene activation of human REL proto-oncogene, NF-kB subunit 1 kit
$1,657.00
KN211878 REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211878BN REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211878RB REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411878 REL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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