Human c Rel (REL) activation kit by CRISPRa

SKU
GA104063
REL CRISPRa kit - CRISPR gene activation of human REL proto-oncogene, NF-kB subunit
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol REL
Locus ID 5966
Components

GA104063G1, c Rel gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104063G2, c Rel gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104063G3, c Rel gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001291746, NM_002908
UniProt ID Q04864
Synonyms C-Rel
Summary This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2014
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Other Versions
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KN211878 REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN211878LP REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN211878RB REL - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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