MPRIP Human Gene Knockout Kit (CRISPR)

SKU
KN211386BN
MPRIP - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol MPRIP
Locus ID 23164
Components

KN211386G1, MPRIP gRNA vector 1 in pCas-Guide CRISPR vector

KN211386G2, MPRIP gRNA vector 2 in pCas-Guide CRISPR vector

KN211386BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_015134, NM_201274, NM_001364716
UniProt ID Q6WCQ1
Synonyms M-RIP; MRIP; p116Rip; RHOIP3; RIP3
Summary Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA108086 MPRIP CRISPRa kit - CRISPR gene activation of human myosin phosphatase Rho interacting protein 1 kit
$1,657.00
KN211386 MPRIP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211386LP MPRIP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211386RB MPRIP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411386 MPRIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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