Human MPRIP activation kit by CRISPRa

SKU
GA108086
MPRIP CRISPRa kit - CRISPR gene activation of human myosin phosphatase Rho interacting protein
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MPRIP
Locus ID 23164
Components

GA108086G1, MPRIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108086G2, MPRIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108086G3, MPRIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_015134, NM_201274, NM_001364716
UniProt ID Q6WCQ1
Synonyms M-RIP; MRIP; p116Rip; RHOIP3; RIP3
Summary Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.UniProtKB/Swiss-Prot Function
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Other Versions
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KN211386 MPRIP - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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