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PVRL1 (NECTIN1) Human Gene Knockout Kit (CRISPR)

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SKU
KN211214BN
PVRL1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PVRL1 or NM_002855"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PVRL1
Locus ID 5818
Components

KN211214G1, PVRL1 gRNA vector 1 in pCas-Guide CRISPR vector

KN211214G2, PVRL1 gRNA vector 2 in pCas-Guide CRISPR vector

KN211214BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002855, NM_032767, NM_203285, NM_203286
UniProt ID Q15223
Synonyms CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
Summary This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. provided by RefSeq, Oct 2009
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Documents
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Other Versions
SKU Description Size Price
GA103956 NECTIN1 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 1 1 kit
$1,657.00
KN211214 NECTIN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211214LP PVRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211214RB PVRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411214 NECTIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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