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Human PVRL1 (NECTIN1) activation kit by CRISPRa

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SKU
GA103956
NECTIN1 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 1
  $1,657.00
4 Weeks*

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Other products for "NECTIN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NECTIN1
Locus ID 5818
Components

GA103956G1, PVRL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103956G2, PVRL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103956G3, PVRL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002855, NM_032767, NM_203285, NM_203286
UniProt ID Q15223
Synonyms CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
Summary This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN211214 NECTIN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211214BN PVRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211214LP PVRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211214RB PVRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411214 NECTIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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