B3GALT5 Human Gene Knockout Kit (CRISPR)

CAT#: KN211183LP

B3GALT5 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: B3GALT5
• Locus ID: 10317
• Components:

  KN211183G1, B3GALT5 gRNA vector 1 in pCas-Guide CRISPR vector

  KN211183G2, B3GALT5 gRNA vector 2 in pCas-Guide CRISPR vector

  KN211183LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001278650, NM_006057, NM_033170, NM_033171, NM_033172, NM_033173, NM_001356336, NM_001356338, NM_001356339
• UniProt ID: Q9Y2C3
• Synonyms: 3-GalTase 5; B3GalT-V; B3GalTx; B3T5; beta-1; beta-3-Gx-T5; beta3Gal-T5; GLCT5
• Summary: This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants using multiple alternate promoters have been observed for this gene. [provided by RefSeq, Sep 2017]