PTPRS Human Gene Knockout Kit (CRISPR)

SKU
KN211163RB
PTPRS - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PTPRS
Locus ID 5802
Components

KN211163G1, PTPRS gRNA vector 1 in pCas-Guide CRISPR vector

KN211163G2, PTPRS gRNA vector 2 in pCas-Guide CRISPR vector

KN211163RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002850, NM_130853, NM_130854, NM_130855
UniProt ID Q13332
Synonyms PTPSIGMA; R-PTP-S; R-PTP-sigma
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103946 PTPRS CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type S 1 kit
$1,657.00
KN211163 PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211163BN PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211163LP PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411163 PTPRS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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