Human PTPRS activation kit by CRISPRa

SKU
GA103946
PTPRS CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type S
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRS
Locus ID 5802
Components

GA103946G1, PTPRS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103946G2, PTPRS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103946G3, PTPRS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002850, NM_130853, NM_130854, NM_130855
UniProt ID Q13332
Synonyms PTPSIGMA; R-PTP-S; R-PTP-sigma
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
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KN211163 PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN211163BN PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN211163LP PTPRS - human gene knockout kit via CRISPR, HDR mediated 1 kit
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$1,657.00
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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