TDP43 (TARDBP) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | TDP43 |
| Locus ID | 23435 |
| Components |
KN210639G1, TDP43 gRNA vector 1 in pCas-Guide CRISPR vector KN210639G2, TDP43 gRNA vector 2 in pCas-Guide CRISPR vector KN210639RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_007375 |
| UniProt ID | Q13148 |
| Synonyms | ALS10; TDP-43 |
| Summary | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA108308 | TARDBP CRISPRa kit - CRISPR gene activation of human TAR DNA binding protein | 1 kit |
$1,657.00
|
|
| KN210639 | TARDBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN210639BN | TARDBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN210639LP | TARDBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN410639 | TARDBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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