PVRIG Human Gene Knockout Kit (CRISPR)

SKU KN210470RB

PVRIG - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Vector: RFP-BSD
• Target Symbol: PVRIG
• Locus ID: 79037
• Components:

  KN210470G1, PVRIG gRNA vector 1 in pCas-Guide CRISPR vector

  KN210470G2, PVRIG gRNA vector 2 in pCas-Guide CRISPR vector

  KN210470RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_024070
• UniProt ID: Q6DKI7
• Synonyms: C7orf15
• Summary: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]
• Shipping: Ambient