Human PVRIG activation kit by CRISPRa

SKU GA112328

PVRIG CRISPRa kit - CRISPR gene activation of human PVR related immunoglobulin domain containing

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PVRIG
• Locus ID: 79037
• Components:

  GA112328G1, PVRIG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112328G2, PVRIG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112328G3, PVRIG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024070
• UniProt ID: Q6DKI7
• Synonyms: C7orf15
• Summary: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]