NOX1 Human Gene Knockout Kit (CRISPR)

SKU KN210426LP

NOX1 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: NOX1
• Locus ID: 27035
• Components:

  KN210426G1, NOX1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN210426G2, NOX1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN210426LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001271815, NM_007052, NM_013954, NM_013955
• UniProt ID: Q9Y5S8
• Synonyms: GP91-2; MOX1; NOH-1; NOH1
• Summary: This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
• Shipping: Ambient