NOX1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | NOX1 antibody was raised against a 15 amino acid peptide near the center of human NOX1. |
| Buffer | PBS containing 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | NOX1 antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | Predicted: 62 kDa; Observed: 64 kDa |
| Gene Name | NADPH oxidase 1 |
| Database Link | |
| Background | Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress (1). NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox (1). Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv (2). NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain (1-3). NOX1 have the potential to be effective treatments for a range of ischemic diseases (4). |
| Synonyms | SWIP1; WSB-1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR
Diebold, Wilder, De Deken et al
Methods Mol. Biol. (2019) 1982, 191-229 DOI: 10.1007/978-1-4939-9424-3_12
Diebold, Wilder, De Deken et al
Methods Mol. Biol. (2019) 1982, 191-229 DOI: 10.1007/978-1-4939-9424-3_12
Snippet: Dr. J. David Lambeth Mouse Monoclonal Clone E39 3rd extracellular loop Yesc (IF, IHC) H [13] OriGene Technologies #TA349080 Rabbit Polyclonal Proprietary Nod H
Showing 1-1 of 1 papers.
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