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AMPK alpha 2 (PRKAA2) Human Gene Knockout Kit (CRISPR)

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SKU
KN210226BN
PRKAA2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "AMPK alpha 2 or NM_006252"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol AMPK alpha 2
Locus ID 5563
Components

KN210226G1, AMPK alpha 2 gRNA vector 1 in pCas-Guide CRISPR vector

KN210226G2, AMPK alpha 2 gRNA vector 2 in pCas-Guide CRISPR vector

KN210226BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_006252
UniProt ID P54646
Synonyms AMPK; AMPK2; AMPKa2; PRKAA
Summary The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103755 PRKAA2 CRISPRa kit - CRISPR gene activation of human protein kinase AMP-activated catalytic subunit alpha 2 1 kit
$1,657.00
KN210226 PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210226LP PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210226RB PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN410226 PRKAA2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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