OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human AMPK alpha 2 (PRKAA2) activation kit by CRISPRa

Be the first to review this product
SKU
GA103755
PRKAA2 CRISPRa kit - CRISPR gene activation of human protein kinase AMP-activated catalytic subunit alpha 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA380334 AMPKα2 Rabbit polyclonal Antibody
100 ul
$475.00
RC210226 PRKAA2 (Myc-DDK-tagged)-Human protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2)
10 ug
$771.00

Other products for "PRKAA2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRKAA2
Locus ID 5563
Components

GA103755G1, AMPK alpha 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103755G2, AMPK alpha 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103755G3, AMPK alpha 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_006252
UniProt ID P54646
Synonyms AMPK; AMPK2; AMPKa2; PRKAA
Summary The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. provided by RefSeq, Jul 2008
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN210226 PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210226BN PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210226LP PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210226RB PRKAA2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN410226 PRKAA2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products