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p57 Kip2 (CDKN1C) Human Gene Knockout Kit (CRISPR)

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SKU
KN209840LP
CDKN1C - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "p57 Kip2 or NM_000076"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol p57 Kip2
Locus ID 1028
Components

KN209840G1, p57 Kip2 gRNA vector 1 in pCas-Guide CRISPR vector

KN209840G2, p57 Kip2 gRNA vector 2 in pCas-Guide CRISPR vector

KN209840LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000076, NM_001122630, NM_001122631, NM_001362474, NM_001362475
UniProt ID P49918
Synonyms BWCR; BWS; KIP2; p57; p57Kip2; WBS
Summary This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Oct 2010
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Other Versions
SKU Description Size Price
GA100740 CDKN1C CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase inhibitor 1C 1 kit
$1,657.00
KN209840 CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209840BN CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209840RB CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409840 CDKN1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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