Human p57 Kip2 (CDKN1C) activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CDKN1C |
| Locus ID | 1028 |
| Components |
GA100740G1, p57 Kip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100740G2, p57 Kip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100740G3, p57 Kip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_000076, NM_001122630, NM_001122631, NM_001362474, NM_001362475 |
| UniProt ID | P49918 |
| Synonyms | BWCR; BWS; KIP2; p57; p57Kip2; WBS |
| Summary | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Oct 2010 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN209840 | CDKN1C - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN209840BN | CDKN1C - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN209840LP | CDKN1C - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN209840RB | CDKN1C - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN409840 | CDKN1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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