Human p57 Kip2 (CDKN1C) activation kit by CRISPRa

SKU
GA100740
CDKN1C CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase inhibitor 1C
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDKN1C
Locus ID 1028
Components

GA100740G1, p57 Kip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100740G2, p57 Kip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100740G3, p57 Kip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000076, NM_001122630, NM_001122631, NM_001362474, NM_001362475
UniProt ID P49918
Synonyms BWCR; BWS; KIP2; p57; p57Kip2; WBS
Summary This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Oct 2010
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Other Versions
SKU Description Size Price
KN209840 CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209840BN CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209840LP CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209840RB CDKN1C - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409840 CDKN1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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