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PRPK (TP53RK) Human Gene Knockout Kit (CRISPR)

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SKU
KN209748RB
TP53RK - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PRPK or NM_033550"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PRPK
Locus ID 112858
Components

KN209748G1, PRPK gRNA vector 1 in pCas-Guide CRISPR vector

KN209748G2, PRPK gRNA vector 2 in pCas-Guide CRISPR vector

KN209748RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_033550
UniProt ID Q96S44
Synonyms BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p; PRPK
Summary Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA114374 TP53RK CRISPRa kit - CRISPR gene activation of human TP53 regulating kinase 1 kit
$1,657.00
KN209748 TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209748BN TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209748LP TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409748 TP53RK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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