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Human PRPK (TP53RK) activation kit by CRISPRa

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SKU
GA114374
TP53RK CRISPRa kit - CRISPR gene activation of human TP53 regulating kinase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA808232 TP53RK mouse monoclonal antibody, clone OTI5B2 (formerly 5B2) 100 ul
$447.00
RC209748 TP53RK (Myc-DDK-tagged)-Human TP53 regulating kinase (TP53RK)
10 ug
$300.00

Other products for "TP53RK"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TP53RK
Locus ID 112858
Components

GA114374G1, PRPK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114374G2, PRPK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114374G3, PRPK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_033550
UniProt ID Q96S44
Synonyms BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p; PRPK
Summary Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN209748 TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209748BN TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209748LP TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209748RB TP53RK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409748 TP53RK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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