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TIM 3 (HAVCR2) Human Gene Knockout Kit (CRISPR)

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SKU
KN209440
HAVCR2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "TIM 3 or BC020843"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol TIM 3
Locus ID 84868
Components

KN209440G1, TIM 3 gRNA vector 1 in pCas-Guide CRISPR vector

KN209440G2, TIM 3 gRNA vector 2 in pCas-Guide CRISPR vector

KN209440D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_032782
UniProt ID Q8TDQ0
Synonyms CD366; HAVcr-2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. provided by RefSeq, Sep 2011
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Other Versions
SKU Description Size Price
GA113725 HAVCR2 CRISPRa kit - CRISPR gene activation of human hepatitis A virus cellular receptor 2 1 kit
$1,657.00
KN209440BN HAVCR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209440LP HAVCR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209440RB HAVCR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409440 HAVCR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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