TIM 3 (HAVCR2) Mouse Monoclonal Antibody [Clone ID: OTI2E2]
Specifications
| Product Data | |
| Clone Name | OTI2E2 |
|---|---|
| Application | WB |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22-202 of human HAVCR2(NP_116171) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 33.2 kDa |
| Gene Name | hepatitis A virus cellular receptor 2 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. provided by RefSeq, Sep 2011 |
| Synonyms | CD366; HAVcr-2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3 |
| Reference Data | |
| Protein Categories | CD Markers, Chemokines, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
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Resources
Other "OTI2E2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF807034 | Carrier-free (BSA/glycerol-free) HAVCR2 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2) | 100 ug |
$620.00
|
|
| TA807034AM | HAVCR2 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2), Biotinylated | 100 ul |
$509.00
|
|
| TA807034BM | HAVCR2 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2), HRP conjugated | 100 ul |
$509.00
|
|
| TA807034S | HAVCR2 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2) | 30 ul |
$200.00
|
|
Citations
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