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MMP14 Human Gene Knockout Kit (CRISPR)

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SKU
KN208917BN
MMP14 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC208917 MMP14 (Myc-DDK-tagged)-Human matrix metallopeptidase 14 (membrane-inserted) (MMP14)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "MMP14 or NM_004995"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol MMP14
Locus ID 4323
Components

KN208917G1, MMP14 gRNA vector 1 in pCas-Guide CRISPR vector

KN208917G2, MMP14 gRNA vector 2 in pCas-Guide CRISPR vector

KN208917BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004995
UniProt ID P50281
Synonyms MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS
Summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA102943 MMP14 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 14 1 kit
$1,657.00
KN208917 MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208917LP MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208917RB MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408917 MMP14 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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