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Human MMP14 activation kit by CRISPRa

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SKU
GA102943
MMP14 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 14
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC208917 MMP14 (Myc-DDK-tagged)-Human matrix metallopeptidase 14 (membrane-inserted) (MMP14)
10 ug
$812.00

Other products for "MMP14"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMP14
Locus ID 4323
Components

GA102943G1, MMP14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102943G2, MMP14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102943G3, MMP14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_004995
UniProt ID P50281
Synonyms MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS
Summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN208917 MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208917BN MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208917LP MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208917RB MMP14 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408917 MMP14 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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