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STING (TMEM173) Human Gene Knockout Kit (CRISPR)

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SKU
KN208418LP
TMEM173 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "STING or AK095896"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol STING
Locus ID 340061
Components

KN208418G1, STING gRNA vector 1 in pCas-Guide CRISPR vector

KN208418G2, STING gRNA vector 2 in pCas-Guide CRISPR vector

KN208418LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001301738, NM_198282, NM_001367258
UniProt ID Q86WV6
Synonyms ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING
Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
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Documents
Resources
Other Versions
SKU Description Size Price
GA117456 TMEM173 CRISPRa kit - CRISPR gene activation of human transmembrane protein 173 1 kit
$1,657.00
KN208418 TMEM173 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208418BN TMEM173 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208418RB TMEM173 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408418 TMEM173 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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