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CHRFAM7A Human Gene Knockout Kit (CRISPR)

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SKU
KN207623BN
CHRFAM7A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "CHRFAM7A or NM_139320"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol CHRFAM7A
Locus ID 89832
Components

KN207623G1, CHRFAM7A gRNA vector 1 in pCas-Guide CRISPR vector

KN207623G2, CHRFAM7A gRNA vector 2 in pCas-Guide CRISPR vector

KN207623BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_139320, NM_148911
UniProt ID P36544
Synonyms CHRNA7; CHRNA7-DR1; D-10
Summary The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA113936 CHRFAM7A CRISPRa kit - CRISPR gene activation of human CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 1 kit
$1,657.00
KN207623 CHRFAM7A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207623LP CHRFAM7A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207623RB CHRFAM7A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407623 CHRFAM7A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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