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GPNMB Human Gene Knockout Kit (CRISPR)

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SKU
KN207615LP
GPNMB - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "GPNMB or BC011595"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol GPNMB
Locus ID 10457
Components

KN207615G1, GPNMB gRNA vector 1 in pCas-Guide CRISPR vector

KN207615G2, GPNMB gRNA vector 2 in pCas-Guide CRISPR vector

KN207615LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001005340, NM_002510
UniProt ID Q14956
Synonyms HGFIN; NMB
Summary The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
GA107133 GPNMB CRISPRa kit - CRISPR gene activation of human glycoprotein nmb 1 kit
$1,657.00
KN207615 GPNMB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207615BN GPNMB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207615RB GPNMB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407615 GPNMB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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