beta 2 Microglobulin (B2M) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | beta 2 Microglobulin |
| Locus ID | 567 |
| Components |
KN207587G1, beta 2 Microglobulin gRNA vector 1 in pCas-Guide CRISPR vector KN207587G2, beta 2 Microglobulin gRNA vector 2 in pCas-Guide CRISPR vector KN207587LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_004048 |
| UniProt ID | P61769 |
| Synonyms | IMD43 |
| Summary | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.provided by RefSeq, Aug 2014 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA100388 | B2M CRISPRa kit - CRISPR gene activation of human beta-2-microglobulin | 1 kit |
$1,657.00
|
|
| KN207587 | B2M - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN207587BN | B2M - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN207587RB | B2M - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN407587 | B2M - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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