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OTX2 Human Gene Knockout Kit (CRISPR)

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SKU
KN207479LP
OTX2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "OTX2 or NM_001270523"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol OTX2
Locus ID 5015
Components

KN207479G1, OTX2 gRNA vector 1 in pCas-Guide CRISPR vector

KN207479G2, OTX2 gRNA vector 2 in pCas-Guide CRISPR vector

KN207479LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001270523, NM_001270524, NM_001270525, NM_021728, NM_172337, NR_073034, NR_073036
UniProt ID P32243
Synonyms CPHD6; MCOPS5
Summary This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. provided by RefSeq, Jul 2012
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Resources
Other Versions
SKU Description Size Price
GA103345 OTX2 CRISPRa kit - CRISPR gene activation of human orthodenticle homeobox 2 1 kit
$1,657.00
KN207479 OTX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207479BN OTX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207479RB OTX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407479 OTX2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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