LZTFL1 Human Gene Knockout Kit (CRISPR)

SKU
KN207289BN
LZTFL1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol LZTFL1
Locus ID 54585
Components

KN207289G1, LZTFL1 gRNA vector 1 in pCas-Guide CRISPR vector

KN207289G2, LZTFL1 gRNA vector 2 in pCas-Guide CRISPR vector

KN207289BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001276378, NM_001276379, NM_020347, NR_075080
UniProt ID Q9NQ48
Synonyms BBS17
Summary This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. provided by RefSeq, Aug 2020
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Other Versions
SKU Description Size Price
GA110191 LZTFL1 CRISPRa kit - CRISPR gene activation of human leucine zipper transcription factor like 1 1 kit
$1,657.00
KN207289 LZTFL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207289LP LZTFL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207289RB LZTFL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407289 LZTFL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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