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PARP1 Human Gene Knockout Kit (CRISPR)

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SKU
KN207085BN
PARP1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PARP1 or NM_001618"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PARP1
Locus ID 142
Components

KN207085G1, PARP1 gRNA vector 1 in pCas-Guide CRISPR vector

KN207085G2, PARP1 gRNA vector 2 in pCas-Guide CRISPR vector

KN207085BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001618
UniProt ID P09874
Synonyms ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL
Summary This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA100098 PARP1 CRISPRa kit - CRISPR gene activation of human poly(ADP-ribose) polymerase 1 1 kit
$1,657.00
KN207085 PARP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207085RB PARP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407085 PARP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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