Human PARP1 activation kit by CRISPRa

SKU
GA100098
PARP1 CRISPRa kit - CRISPR gene activation of human poly(ADP-ribose) polymerase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PARP1
Locus ID 142
Components

GA100098G1, PARP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100098G2, PARP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100098G3, PARP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001618
UniProt ID P09874
Synonyms ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL
Summary This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. provided by RefSeq, Jul 2008
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Resources
Other Versions
SKU Description Size Price
KN207085 PARP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN207085BN PARP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207085RB PARP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407085 PARP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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